Forskolin is an ingredient found in the Indian coleus plant, also known as Coleus forskohlii. It is a labdane diterpene that is currently very popular as a nutritional supplement, predominantly in the body building circles. The ability to raise the levels of cyclic adenosine monophosphate, cAMP, by deploying the enzyme adenylyl cyclase in the cAMP dependent pathway, made forskolin very important. Further benefits of forskolin include reduction of urinary tract infections, in connection with rolipram inhibition of colon cancer spreading, stimulation of proper tanning response with increased skin resistance to sun burns, reduction of intraocular pressure in glaucoma cases and apparently assistance in weight loss programs. Forskolin was observed to increase bone and lean mass as well as testosterone levels in clinical trials conducted with human test subjects.

Tribulus Terrestris is derived from a vine plant that grows on tropical climates. The plant may be found in the countries of China, India, Mexico and Eastern Europe. It has many medicinal properties. It is traditionally used by the Chinese for it ability to treat headaches, dizziness, clam the liver and improve sexual problems. It contains phytosterols, saponins, glycosides, and spirostanol. Tribulus Extract stimulates the production and secretion of testosterone that plays an important part in muscle formation and development. It also helps improve the libido and prevents impotence. It enhances the mood and energy level. Tribulus Extract also aids in lowering the blood cholesterol level.

Vitex agnus-castus is commonly called vitex. It is also known by its other names such as chaste tree, chasteberry or monk’s pepper. It is plant which is native to the Mediterranean region. Since it has aromatic foliage and flowers, it is cultivated in warm and subtropical regions. In Africa, vitex is a traditional but little known plant. It boosts of food security and also has the potential of improving nutrition. It is also used for foster rural development and it also supports sustainable land care. During pregnancy, the usage of vitex agnus-castus might increase the chance of complications. Therefore, it should be avoided during pregnancy. As it have effects on the testosterone levels, male body builder’s use vitex agnus-castus as a supplement but only as a secondary component.