Caffeine is a xanthine alkaloid that has a psychoactive stimulant effect. It may be found in many plant species but the main source of caffeine is coffee or cocoa bean. It is a potent stimulant that causes the heart rate to increase, muscles to tighten up, and the pupils to dilate. It activates the adrenaline that gives a boost of energy. It also reduces the symptoms of asthma. It helps open up the airways for ease of breathing. It increases the metabolism and breaks down fats. It also helps increase muscle strength. It also prevents chronic fatigue syndrome. Caffeine helps ease headache. It also reduces the risk of diabetes, Parkinson’s disease, and colon cancer.

Ephedra Extract is extracted from the plant Ephedra sinica, It has been used in traditional Chinese medicine for the treatment of asthma and hay fever. Ephedra is used both as a stimulant and a thermogenic, which stimulates the brain, increases heart rate, increases blood pressure and expands bronchial tubes (making breathing easier). These effects are due to its ephedrine and pseudoephedrine content. Research also shows that it can be used as a precursor in the illicit manufacture of methamphetamine. Ephedra extracts are also used by athletes to enhance athletic performance. It is also used in supplements for weight loss.

Hoodia Gordonii is widely thought of as an appetite suppressant; however, there have not been sufficient studies to support this theory.

L-Tyrosine is an amino acid that is nonessential. It is synthesized from the body from phenylalanine which is also an amino acid. L-Tyrosine has the power to have an effect on the neurotransmitters and this affects various health conditions including depression, mood disorders and Parkinson’s disease. Many such studies have proved that L-Tyrosine helps people having depression. It acts as a precursor and eases the effects of psychosocial, environmental and physical stress. L-Tyrosine turns into melanin by the skin cells and the dark pigment prevents the ultraviolet light from affecting. The thyroid hormones playing a significant role in the process of the body also contain tyrosine. L-Tyrosine is commonly found in all the dairy products, fish, oats, wheat, meat and also in all other protein containing foods. This is also found to be beneficial for people trying to withdraw alcohol. L-Tyrosine has not exhibited severe side effects, yet taking it should be recommended by doctors.

Phenylethlamine HCL is a salt of phenylethylamine. It is a crystalline solid and is formed by treating phenylethylamine with HCl. Its IUPAC name is 2 phenylethylamine HCl. The scientific name elucidates its chemical structure. It is an aromatic compound meaning that it has a basic benzene ring. It further has a two carbon chain attached at position 2 of the ring and the chain terminates in an amino group. It occurs naturally in some foods like chocolates but the food item might get metabolized too quickly sometimes for it to have a significant effect on the body. This substance has quite profound effects on the level of dopamine in the central nervous system, provided it passes the blood brain barrier. It increases dopamine level and at the same time inhibits dopamine transmitters resulting in a buildup of dopamine in the brain. While excessive levels of dopamine in the CNS are not healthy, the neurotransmitter does regulate cognition, mood, voluntary movement and other brain functions.

Raspberry Ketones come from a common fruit found in numerous countries. It is molecularly similar to capsaicin, found in chilli peppers, which has potent thermogenic properties. Raspberry Ketones greatly help decrease body fat. It helps in treating obesity by decreasing the absorption of fats and increasing norepinephine-induced fat breakdown or lipolysis. It also has the ability to decrease the fats in the liver and visceral adipose tissues. Raspberry Ketones also help control and maintain blood sugar and blood pressure levels. It also help balance the good cholesterol level. It contains significant levels of ellargic acid, a phenolic compound that fights abnormal or cancer cells. It also contains quercetin, flavonols, and anthocyanins that has been found to be effective antioxidants that protects the heart and the skin from age-related decline.

Synephrine is an adrenergic amines and stimulant with beta-3 receptors. It functions to increase metabolic rate with no effect to heart rate or blood pressure. Synephrine releases adrenaline and noradrenalin in the adipose tissue and the liver. Stimulation of the beta-3 receptor sites to educe the breakdown of fat. It can be added to the group of stimulants, to which belong such supplements as caffeine or ephedrine. Can be used to boost energy, suppress appetite and enhance metabolic rate to burn more calories and increased the energy, but it does not cause so undesired negative cardiovascular effects. Its active ingredients include gelatin, cellulose, and silica and magnesium strearate. Its weight loss abilities are associated with citrus aurantium (synephrine) supplements which give it the stimulant like effects of the alkaloids.

Vitamin B6, which active form pyridoxal phosphate or otherwise known as PLP and pyridoxal-5’-phosphate, is a prosthetic group of tightly bound cofactors responsible for many reactions within the amino acid metabolism and the manipulation of the enzymatic reaction behind the release of glucose from glycogen. Vitamin B6 generally comprises three organic compounds, pyridoxine, pyridoxal and pyridoxamine, all of them heterocyclic organic compounds that are converted in the human body to the active pyridoxal phosphate form. There are three reactions attributed to PLP, namely transamination, alpha elimination and beta elimination. Over one hundred and forty enzyme activities depend on pyridoxal phosphate, neurotransmitter and histamine synthesis, synthesis and function of hemoglobin, and gene expression. As a cofactor, PLP is active in amino acid metabolism, glucogenesis and lipid metabolism.

White Willow Bark, or Salix alba, is a willow commonly found in Europe and adjacent parts of western and central Asia. The bark of the White Willow has been used for centuries against fevers and to ease pains and aches. Already Hippocrates wrote about the White Willow bark powder two thousand five hundred years ago. The active ingredient of the White Willow bark is called salicin, a relative to aspirin and chemical derivative of the salicylic acid. When ingested, salicin is converted to salicylic acid, a beta hydroxy acid. As a nutritional supplement, White Willow products are being propagated as weight loss additives, whereby the scientific community has yet to provide any corroboration to this allegation. Besides the well known anti inflammatory characteristics, any other uses have not been approved by the FDA.