Grape seed is the seeds of the ordinary grapes. They are used primarily because they have polyphenols recognized as anti oxidants. Research confirms numerous health benefits of grape seed extracts; they limit lipid oxidation, thus controlling high blood pressure and high cholesterol levels. Grape seeds contain phenolics, which are useful in treatment of heart disease because they inhibit platelet aggregation and reduce inflammation, however, the results are preliminary and more research is being done to confirm these facts. A polyphenol contained in grape seeds is resveratrol which may inhibit cancer cell growth and proliferation, and it may also be active against HIV by inhibiting expression and replication of the genome of the virus.