Caffeine is a powerful and very common alkaloid supplement used in Estrin-D primarily to increase the body’s ability to lose weight quickly, boost energy and stimulate the brain into more activity with better clarity. It also fuels the body’s metabolism for increased fat burning qualities. This allows users to have more stamina for exercise and more focus for weight loss initiatives. Caffeine anhydrous is found naturally in many different beans and plants and works successfully as a stimulating supplement for those needing increased energy, focus, and alertness. When taken as a supplement for health or weight loss reasons, caffeine anhydrous should not be combined with other traditional forms of caffeine, such as soft drinks, energy drinks, coffee, or tea, because the supplement form is concentrated and powerful in itself.

Ginger Root- Ginger is a very popular spice and has been used for culinary purposes for ages. Besides the widespread use in the cuisine of many nations, several traditional medicines, including the Indian and Chinese medicinal practices, have used this Zingiber officinale, as the Latin name goes, for its pain relieving, anti allergenic and anti inflammatory activities. Further uses have been noted for treatment of various ailments of the digestive tract, such as diarrhea and nausea, but also as general stomach settlers. While the use of the ginger root extract has been used in ginger beer and ginger ale beverages, the use as dietary supplement or component in nutritional supplement concoctions is relatively recent. The volatile oils of the ginger root extract have been noted for the antibacterial, analgesic, sedative and antipyretic properties.

Green Tea Extract increases energy expenditure and affects fat oxidation, which therefore promotes weight loss by increasing the body's metabolism.

Guarana, a stimulant derived from the seeds of the Brazilian Guarana plant. Guarana is used to increase alertness and help fight fatigue. It contains caffeine and is usually associated with an "energy crash" several hours after taking a large dose.

Kola Nut- The trees found in Africa have seed pods that are inherent with Kola nuts. In regions of western Africa and central Africa, Kola nut trees are commonly found and they tend to grow up to 18 meters in height which is a good 60 feet. Kola nut consists of caffeine and has acts as a powerful anti depressant and stimulant. Kola nuts importance has been realized mainly in western Africa. It is also useful in reducing indigestion, hunger and fatigue. In simple words, it functions as an aphrodisiac. According to tradition, Kola nuts are offered when someone enters their new house and it symbolizes hospitality and friendship. Kola nut can be easily found as there are several street vendors selling them at places such as the bus or train station.

Some Unknown Ingredients, which is a common practice for many supplement manufacturers. They use ineffective common ingredients and trademark their name for them to disguse the actual low quality ingredient contained.

Yerba Matte has a level of caffeine and is therefore a stimulant aids in toning, balancing and strengthening the body, aids in digestion, calms and balances nerves and is also used to help treat allergies and sinusitis.