Chromium Polynicotinate is a nutritional supplement designed primarily as nutritional support for certain conditions that are typical for sufferers from diabetes mellitus type 2 or age related diabetes. Recent studies have revealed that supplemented chromium can reduce high blood glucose levels, lowering or eliminating nonenzymatic glycation. Further studies reveal that supplementing chromium polynicotinate can help with depression symptoms as well as reduce systolic blood pressure elevation caused by sucrose. People with chromium deficiencies have trouble maintaining stable blood sugar levels. Chromium polynicotinate can assist in regulating the levels of blood sugar, but it also helps with the control of cholesterol, promote the fat removal process and encourage buildup of lean muscles. For these characteristics it is a popular supplement for body building and any muscle building sports enthusiasts.

Garcinia Cambogia, native to Southeast Asia, is a tropical fruit which belongs to the citrus family. This Indian and African fruit is extremely popular for its extract hydroxycitric acid. Without suppressing your appetite or stimulating the brain, this acid acts as an effective weight loss supplement. It not only provides the required energy but also improves the signaling system of the body. When the signaling system gets better, the brain is informed by the body that it is full. This system is not very active in obese people, which is why they eat a lot. Garnicia Cambogia extract of hydroxycitric acid is more effectual when used with chromium. The intake of chromium in western countries is very low, due to which people become diabetic or obese.

Guarana, a stimulant derived from the seeds of the Brazilian Guarana plant. Guarana is used to increase alertness and help fight fatigue. It contains caffeine and is usually associated with an "energy crash" several hours after taking a large dose.

Hoodia Gordonii- Mainly grown in the regions of South Africa, Hoodia Gordoni similar to a cactus plant with no leaves is used for medical purposes. It has been more popularly used for weight loss purposes. In spite of it resembling a cactus plant, Hoodia Gordoni is actually a juicy Plant. It’s most famous for its unique ingredient named as “steroidal glycoside”, which is supposedly to be found only in Hoodia Gordoni. You could easily find one at a health store or may be in some famous diet pill such as “Trimspa”. A common misconception is that Hoodia Gordoni has no side effects, however it has been suggested that people with diabetes should be careful, while taking Hoodia Gordoni. It has the capacity to not only repress your appetite, but also your thirst. This can be dangerous as our body would feel dehydrated.

Synthetic Guggulsteroneswere first intended for use as a drug and is now used as a weight loss product and weight management product with the possibility of some side effects. More studies need to be done on this.