Bioperine is derived from the extract of Piper nigrum L (black pepper) or Piper longum L (long pepper). Bioperine activates the thermogenesis process that generates energy at the cellular level. This process also helps in burning of fats. It also increases the absorption of nutrients and vitamins. It ensures that the body benefits and is able to efficiently use the nutrients from the food. It also boosts the metabolism that makes it effective in weight loss and maintenance. Because of the boost in metabolism, it also provides the body an increased supply of energy. It also aids in the proper digestion.

Evodiamine, an alkaloid extract from the Evodiae Fructus plant is known as Evodiamine. It has been referred to as a “hot nature” herb in Chinese literature and medicine. Based on animal studies, Evodiamine increases the natural fat burning rate and stimulates vanilloids for reduction of fat intake. It increases body temperature, influences the adrenal glands to secrete catecholamines and also affects the metabolism of certain drugs. Since it acts like a thermogenic and increases the overall temperature, more fat and calories are burnt due to its intake. This alkaloidal compound has anti obesity effects due to UCP1 (uncoupling protein 1) thermogenesis. In part, evodiamine can prevent diet induced obesity from developing further. It is available in the form of supplement or through Evodiae Fructus plant.

Green Tea Extract- Camellia sinensis, or more commonly the tea plant is a genus of flowering plants which is generally being used to produce tea, including green tea, oolong, black tea, white tea and pu-erh tea, also called Bolay tea. The different oxidation process makes the final difference. Tea plants can grow out into a tree, but are generally pruned to allow for easy hand picking. While camellia sinensis is being cultivated all around the globe in tropical and subtropical regions, this South and Southeast Asian native is most popular when imported from India and China. Medical uses of tea stem from the traditional Chinese medicine, where it was used as a bronchodilator and to treat angina pectoris, coronary artery disease and peripheral vascular diseases. Green tea extract is used as appetite suppressant and thermogenesis increasing agent.

Guggulsterone- Commiphora wightii, or the so called Guggul tree is a flowering shrub or rather a small tree which can grow up to a size of 4 meters. Once very common in India, it is now there listed as endangered, but not in northern Africa or elsewhere in central Asia. It was very popular in the Indian Ayurvedic medicine, but also currently in the western medicine for treating of heart problems. The hydrocarbon secretion of Guggul contains a plant sterol, guggulsterone, which in the human body seems to act as an antagonist to the farnesoid X receptor. Furthermore, guggulsterone is active in increasing the natural thyroid production. This in turn stimulates the metabolism and may raise the body temperature, burning stored excess fat.

Hoodia Gordonii, which although popular, has no published randomized controlled trials in humans to show hoodia is safe or effective in pill form. One study published in the September 2004 issue of Brain Research found that injections of p57 (The Active ingredient in Raw, Fresh Cut Hoodia, not dried) into the appetite center of rat brains resulted in altered levels of ATP, an energy molecule that may affect hunger. The animals receiving the P57 injections also ate less than rats that received placebo injections. However, this was an animal study and INJECTIONS IN THE BRAIN are very different from oral consumption, so it cannot be used to show that oral hoodia can suppress appetite in humans. Hoodia Gordonii is a succulent (a cactus of the aloe family) found in the Kalahari desert of South Africa. Most Hoodia Gordonii products contain very little, if any of the active ingredient needed to suppress hunger. Real Hoodia is very rare and is even an endangered plant. Most importantly, Hoodia has only demonstrated any effect in fresh, raw pieces of the plant. The effectiveness of powdered Hoodia has yet to be shown and may actually increase hunger. It's main use is as a cheap alternative to the more expensive weight loss herbs, which are the only alternative left after the banning of ephedra. Most supplement manufacturers can not use the more expensive weight loss herbs because it will result in a product that would be too expensive to compete with other more popular inexpensive diet supplements.

Kelp, which describes any of several large broad-fronded brown seaweeds. Kelp seaweeds are rich sources of minerals and trace elements, especially iodine, which is essential to the proper functioning of the thyroid gland.

L-Tyrosine is a proteinogenic polar amino acid, deemed not essential because it can be synthesized by the human body. As a member of the amino acid group that is being used by cells to build proteins, this building block derived its name from the Greek word tyros, which means cheese, because it was discovered in the cheese protein casein. L-Tyrosine can be synthesized from phenylalanine and can be found in foods high on protein, like soy products, poultry, cheese, bananas, dairy products and several seeds, including the sesame seeds. The unique phenol functionality and the occurrence in proteins that belong to the signal transduction process, make this amino acid different. Tyrosine can be converted by tyrosine hydroxylase enzyme into levodopa, a psychoactive drug that is used, among other uses, for clinical treatment of Parkinson’s disease. It is also involved in the synthesis of dopamine, norepinephrine and epinephrine.

Niacin is a vitamin that wards against pellagra, a disease characterized by a vitamin B3 deficiency. Niacin is made from pyridine and is often called vitamin B3 or nicotinamide, because they all three have similar formulas. Niacin and nicotinamide are comparable in make up, but only niacin works to lower cholesterol levels. The restoration of DNA is also known to be a positive side effect of taking niacin. A fairly large number of individuals, particularly those in third world countries or those suffering from alcoholism, have been shown to be lacking in niacin. Niacin is often taken as a supplement by those with high cholesterol levels, as it has been proven to lower “bad” cholesterol and raise “good” cholesterol.

Oil of Clove.

Pantothenic Acid, also called vitamin B5, which is a water-soluble vitamin required by the human body. Pantothenic acid is needed to form coenzyme-A (CoA), and is vital in the metabolism and synthesis of carbohydrates, proteins, and fats.

Pyridoxine Hydrochloride.

Rhodiola can help increase resistance against fatigue and can reduce stress. Classified as adaptogens among the herbs, it prevents different harmful impacts caused by physical and mental stress and illness. Rhodiola Rosea is particularly helpful for athletes because of its adaptogenic properties and its capability to enhance efficiency of mitochondrial respiration in skeletal muscle. It also improves mental work capacity and resists mental fatigue. Research has found that it helps protect against cancer. It can also be beneficial for people who suffer from high altitude sickness. Its intake can better endurance exercise capacity in young people and may also benefit people suffering from certain kinds of glucose level and cardiac conditions. Rhodiola Rosea helps prevent ischemic brain damage development.

Riboflavin, also called Vitamin B2, is naturally manufactured by the body. Riboflavin is needed for the proper use of oxygen and amino acids, carbohydrates and fatty acids. Riboflavin is also utilized by Vitamin B6 in the body and is used to manufacture niacin. Riboflavin is especially needed when eating large amounts of protein.

Thiamine, also called Vitamin B1 or Thiamin, is needed to help the body utilize energy from proteins, fats and carbohydrates. Thiamine is commonly found in breads and cereals. Thiamine is water-soluble and is concentrated in muscle tissue as it passes thru the body.

Vinpocetine, a derivative alkaloid of vincamine, is actually semi synthetic in nature. It is an extract from the It is an extract from the periwinkle vinca minor. Vinpocentine is used because it has neuroprotective effects and also helps in enhancing the cerebral blood flow. In Eastern Europe, it is also used as a drug to treat cerebrovascular disorders along with age related memory impairment. It is also extensively marketed as a supplement for vasodilation. It is also used to improve the memory since it plays the role of a nootropic. Vinpocentine is therefore used in supporting brain function. It helps in enhancing concentration and memory by activating cerebral metabolism. In the body building world, vinpocetine is often used a vasodilator. However, no research has been done so far on the effect of vinpocentine in the body building.

Vitamin B12- Also called Riboflavin, B2 is a water absorbed vitamin of which the body must replenish its supplies each day as it cannot be stored. It is necessary for the production of red blood cells and, like the other B vitamins, it works at supporting it supports energy production by helping in the metabolism of various foods.B2 is required for healthy skin as well as hair growth, the nails and has a role in regulating the activity of the thyroid gland. It is also necessary in order that the body can process amino acids found in proteins and fats and to activate vitamin B6 and folic acid.